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Description
SEC23B Recombinant Rabbit mAb (S-1935-28)Product Specification Host Rabbit Antigen SEC23B Synonyms Protein transport protein Sec23B; hSec23B; SEC23 related protein B Immunogen Synthetic Peptide Location Cytoplasm, Endoplasmic reticulum Accession Q15437 Clone Number S 1935 28 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC Reactivity Hu, Ms, Rt Positive Sample K562, Raji, MDA MB 231, MCF7, SW620, RAW264. 7, NIH 3T3, C6 Purification Protein A Concentration 0. 5 mg ml
Product Specification
| Host | Rabbit |
| Antigen | SEC23B |
| Synonyms | Protein transport protein Sec23B; hSec23B; SEC23-related protein B |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Endoplasmic reticulum |
| Accession | Q15437 |
| Clone Number | S-1935-28 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | K562, Raji, MDA-MB-231, MCF7, SW620, RAW264.7, NIH/3T3, C6 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt |
| IHC-P | 1:250 | Hu, Ms, Rt |
| ICC | 1:500 | Hu |
Background
SEC23B, also known as Sec23 homolog B, is a crucial component of the coat protein complex II (COPII), which is involved in the transport of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus. This gene plays a significant role in cellular processes such as autophagy regulation and cell migration. Recent studies have shown that SEC23B can induce autophagy in breast cancer cells by inhibiting the ERK/mTOR signaling pathway, thereby promoting cancer cell metastasis. Additionally, SEC23B has been implicated in various cancers, including thyroid cancer, hepatocellular carcinoma, and prostate cancer, suggesting its potential as a therapeutic target.
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4.6 ★★★★★
Based on 1263 reviews
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Product Reviews
★★★★★ 5
Wait to see
I am just starting to use it and I have to use it for a couple of weeks to help me know if it’s works but what I notice after applying it to my hair it’s just makes it so smooth and soft
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 13, 2026
★★★★★ 5
Better than expected
Better than expected, I am absolutely pleased with this product. My bald spot starting showing signs of growth after the first week.
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Reviewed in the United States on January 4, 2026
★★★★★ 5
Lashes like Garbo
Size: 0.27 Fl Oz (Pack of 1), Style: Mascara/Lash Primer, Size: 0.27 Fl Oz (Pack of 1), Style: Mascara/Lash Primer
I think this might be my new go to mascara.
I have the teeniest tiniest lashes ever, they are straight and stick out from my eyelids and without mascara I look like I have no lashes so it’s a struggle finding mascaras that make my lashes look lush.
Let me start off by saying that the primer is amazing.
As soon as I put it on my lashes grew over twice in length!
It didn’t clump and separated my lashes like whoa( the clumping with these lash fiber or extra lengthening mascaras is always horrendous so that was a wonderful surprise), it dried in about 20 seconds and then I put on the coal black mascara.
Vavoom ladies!
Instant fabulous lashes.
So far I have experienced zero flaking after wearing for long periods of time , it hasn’t smudged or melted when I’m dancing up a storm or getting my workout on and the length of my lashes is practically miraculous.
It is not cry proof.
It’s super easy to remove and doesn’t tear out any of my eyelashes though, so that’s another plus!
Also, I have celiac disease and a host of other random allergies and am allergic to SO MANY products it’s ridiculous, but luckily I am not allergic to this magic mascara.
I recently discovered that this doesn’t smudge on my bottom lashes either!
I’m almost 40 and I have never found a mascara that didn’t smudge on my bottom lashes. I’m so oily that even waterproof ones didn’t work!
I stopped wearing it on my bottom lashes for anything but photo shoots after 20yrs old because the smudging made me look like an old lady with terrible makeup skills,but now I can once again rock liner on my bottom lashes!
I included a terrible picture ( I hate getting my picture taken!) and tried to crop it so you can get an idea of how amazing this mascara is( look at those lashes practically touching my brow bone!),because I know I always want to actually see the results of people using the product, so hopefully it helps. :-)
Ps: I don’t have mascara on my bottom lashes in the pic as I didn’t discover it was even a possibility for me until I bought a tube for my bestie ( another oily faced queen)and she told me there was no smudging:-O
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Reviewed in the United States on March 21, 2019
★★★★★ 5
Great mascara, my new favorite!
Size: 0.27 Fl Oz (Pack of 1), Style: Mascara/Lash Primer
I think this is my favorite mascara of all time! lol!
Goes on very easy and not clumping. Makes my eyelashes look longer.
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Reviewed in the United States on June 3, 2026
★★★★★ 4
Mascara is good, but don’t expect the best - smudges & flakes sometimes
Size: 0.27 Fl Oz (Pack of 1), Style: Mascara/Lash Primer
This mascara is very good for lengthening when you use the primer. I’m not sure I’ve noticed a volume/thickness increase, but have noticed lash length does look longer. I usually give it about 30 seconds for the primer to dry before using the mascara, otherwise it does clump a bit. I would also recommend wiggling both wands along your lashes during application to avoid clumps. In general I do like this, but noticed a few other important points: it will definitely run a lot if you get it wet (e.g. rain or crying), it will flake or smudge a little by the end of the day - especially if you rub your eyes, and while it does not make my eyes itch, I found it best to put in my contacts AFTER the mascara is fully dry. I’ve accidentally got some mascara a few times in my eye with the wand/trying to smooth out clumps and it totally made my contacts (daily wear type) useless after that. That all probably sounds like the mascara isn’t worth it, however I still actually like this mascara. I’d say it’s perfect for an average day’s wear, just not an extended day or in some cases. It does come off fully for me.
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Reviewed in the United States on December 31, 2022
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