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Description
Phospho-PKCδ (Thr505) Recombinant Rabbit mAb (S-1668-89)Product Specification Host Rabbit Antigen Phospho PKC (Thr505) Synonyms Protein kinase C delta type; Tyrosine protein kinase PRKCD; nPKC delta; PKCD; PRKCD Immunogen Synthetic Peptide Location Cytoplasm, Nucleus, Mitochondrion, Cell membrane Accession Q05655 Clone Number S 1668 89 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Positive Sample THP 1 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated
Product Specification
| Host | Rabbit |
| Antigen | Phospho-PKCδ (Thr505) |
| Synonyms | Protein kinase C delta type; Tyrosine-protein kinase PRKCD; nPKC-delta; PKCD; PRKCD |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus, Mitochondrion, Cell membrane |
| Accession | Q05655 |
| Clone Number | S-1668-89 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Positive Sample | THP-1 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| Dot Blot | 1:1000 | |
| WB | 1:1000 | Hu |
Background
Phospho-PKCδ (Thr505) refers to the phosphorylation of protein kinase C delta (PKCδ) at threonine residue 505, a modification that is crucial for its activation and function. PKCδ is a member of the protein kinase C (PKC) family, which are serine/threonine kinases involved in various cellular signaling pathways, including regulation of cell growth, apoptosis, and differentiation. The phosphorylation at Thr505 is particularly important for the kinase activity of PKCδ and its role in the G1 to S phase transition during cell cycle progression. This phosphorylation site is specific to PKCδ, and antibodies targeting Phospho-PKCδ (Thr505) do not cross-react with other PKC isoforms, making it a valuable marker for studying PKCδ's unique functions.
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